Janssen study shows benefits of Invokana for diabetes and chronic kidney disease

Pharmaceutical Company Product News

Janssen has announced the findings of a clinical study showing the benefits its drug Invokana can deliver for people with type 2 diabetes and chronic kidney disease.

An additional analysis from the landmark CANVAS programme has shown that Invokana improved renal outcomes in people with type 2 diabetes with or at high risk for cardiovascular disease.

“Janssen has reported new clinical data showing how Invokana offers renal protective benefits for patients with type 2 diabetes and chronic kidney disease.“

This benefit was observed in people with preserved and reduced kidney function, with the drug reducing the urinary albumin to creatinine ratio - a key biomarker for chronic kidney disease.

Following the positive conclusion of this analysis, the company will assess the further benefits of Invokana in a study called CREDENCE, which represents the first dedicated SGLT2 inhibitor trial evaluating renal and cardiovascular outcomes in people with type 2 diabetes and kidney disease.

Dr James List, global therapeutic area head for cardiovascular and metabolism at Janssen Research and Development, said: "We are encouraged that canagliflozin could potentially provide much-needed benefit for those with diabetic kidney disease, and look forward to building further on this insight in CREDENCE."

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