Ketchum has been presented with nine Silver Anvil awards at an annual ceremony held by the Public Relations Society of America (PRSA).
The media agency won more prizes that any other company at the event, with accolades bestowed for media campaigns conducted on behalf of firms such as Philips, Pfizer and FedEx.
It was also able to claim a total of six Awards of Excellence, recognising work done with partners including Kimberly-Clark, Eastman Kodak and Kellogg.
This means that Ketchum has now claimed 126 Silver Anvil awards since the initiative was launched 65 years ago, more than any other firm.
Rob Flaherty, senior partner and president of Ketchum, said: "They underscore the strong partnership we have with our clients and the breakthrough creative, strategic work that leads to meaningful business results."
This comes after the organisation's Ketchum Pleon branch in London was named as one of the top workplaces in the UK by the Great Place to Work Institute.See all the latest jobs in Healthcare Communications