Researchers from Massachusetts Institute of Technology in Boston, have used a study of mice to discover that fasting for 24 hours can reverse the loss of stem cell function in the gut that accompanies ageing. Intestinal stem cells maintain and repair tissue lining in the gut, which renews itself about every 5 days. They are crucial for tissue repair and regeneration, and their decline as we age means that it becomes harder to recover from gastrointestinal conditions and infections. The discovery of a molecule that can activate a metabolic switch, which causes cells to break down fatty acids instead of carbohydrates, could result in drugs that boost older people's recovery from gastrointestinal infections or chemotherapy.
“Fasting for 24 hours can reverse the loss of stem cell function in the gut that accompanies ageing“