Bigger lungs 'linked with better survival rates for transplant patients'

Scientific Developments/Breakthroughs

A US study has demonstrated the benefits of assessing the size of donated lungs when determining which organs should be provided to transplant patients.

The University of Iowa research revealed that oversized lungs are associated with improved survival rates following transplants, particularly among patients receiving double-lung transplants.

“Larger lungs may be associated with improved survival rates among transplant patients, according to a new report.“

It was discovered that using a formula based on predicted total lung capacity (pTLC) ratio can be used to identify organs that can offer benefits in this regard.

For patients undergoing a double-lung transplant, each 0.1 increase in the pTLC ratio was associated with a 7 percent decrease in risk of death a year after the procedure.

Seth Force from the Emory University School of Medicine in Atlanta said: "The data in this manuscript make a compelling argument for the lung transplant community ... to consider changing to a pTLC method for lung sizing for listed patients."

In the UK, there were 165 lung transplants performed between April 2010 and 2011, with the frequency of such procedures being limited by a lack of available donors.

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