| Researchers develop RNA-mapping app for the iPhone | Posted on 02/09/2010 in Scientific Developments/Breakthroughs Scientists at Stanford University have created a new application for the Apple iPhone which allows them to experimentally capture a global snapshot of thousands of RNA molecules within cells.
The application uses deep-sequencing techniques to create a two-dimensional image of the complex structure of the molecules, without the need for complex and time-consuming analysis.
Conducting tests of the technology using baker's yeast, the researchers were able to identify previously undocumented patterns and common structures in RNA which can affect its functioning.
It is hoped that this technology can be expanded upon to provide analysis of more complex RNA structures from different organisms in future.
Dr Howard Chang, associate professor of dermatology at the university, said: "We can leverage this information for biological insight into how RNA structures may change under different conditions. There are levels of complexity that we're only just beginning to understand."
RNA research is becoming an increasingly prominent area in drug development, with Novartis and Quark agreeing a deal last month to jointly produce a p53 temporary inhibitor siRNA drug for kidney transplant patients. Other news stories from 02/09/2010
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