| TTP LabTech: DNA dye to influence future of high content multiplex assay analyses | Posted on 27/11/2007 in Scientific TTP LabTech and Biostatus have revealed data demonstrating the use of DRAQ5 DNA dye in binding assays performed with the Acumen eX3 microplate cytometer.
A far-red fluorescing live cell DNA dye, DRAQ5 has accelerated and improved cell-based drug discovery assays and expanded the repertoire of available analysis on flow cytometers and fluorescence microscopes.
As the degree of multiplexing which can be achieved is hindered when fluorescent probes have spectral profiles that overlap, the Acumen eX3 offers a variety of laser excitation in a single instrument so that a wider range of fluorescent probes can be used.
"DRAQ5 is an ideal cell cycle probe since it offers stoichiometric DNA labelling and far-red fluorescent emission when applied to live or fixed cells," remarked TTP LabTech's chief scientific officer, Dr Wayne Bowen.
"When used in multiplex applications with other fluorophores, there is an exceptional separation between each emission coupled with minimal spectral emission overlap," he continued.
Welcoming the collaborative progression between his firm and Biostatus, Dr Bowen underlined the combination of TTP LabTech's expertise in fluorescent detection instrumentation and Biostatus' ability to develop novel reagent technologies as signalling "an excellent opportunity" to influence the future of high content multiplex assay analyses. Other news stories from 27/11/2007
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